Related Experiment Video
Updated: Oct 2, 2026

Routine Screening Method for Microparticles in Platelet Transfusions
Published on: January 31, 2018
Improving guideline compliance: assessment of unit-based reminder for monitoring platelet counts post-PCI
Daniel Belletti1, Robert B Bolash, Stephen Arcona
1St. Lukes Hospital, USA.
Insights
Implementing reminders improved platelet count monitoring after glycoprotein (GP) IIb/IIIa agent use in cardiac procedures. While compliance didn't fully meet guidelines, the intervention showed a positive impact on monitoring practices.
Area of Science:
- Cardiology
- Clinical Practice Improvement
Background:
- Vascular access site bleeding is a complication after percutaneous coronary interventions (PCI).
- Manufacturer guidelines for glycoprotein (GP) IIb/IIIa agents recommend specific platelet count monitoring, which was anecdotally found to be low.
- Compliance with platelet count monitoring post-PCI using GP IIb/IIIa agents was suboptimal in the catheterization recovery unit (CRU) and coronary care unit (CCU).
Purpose of the Study:
- To assess the effectiveness of a unit-focused reminder system to improve cardiologist compliance with ordering platelet counts after PCI.
- To evaluate changes in platelet count measurement rates following the implementation of a reminder intervention.
Main Methods:
- A reminder system was implemented for cardiologists to order platelet counts post-PCI with GP IIb/IIIa agents.
- Platelet count measurement rates were compared before and after the reminder intervention in the CRU and CCU.
- Compliance with manufacturer guidelines for platelet count monitoring was analyzed.
Main Results:
- The reminder effort led to an increase in the number of patients having platelet counts drawn.
- The CRU demonstrated significant increases in platelet count draws post-reminder for both first and second draws.
- Despite increases, aggregate post-reminder results did not show significant changes in meeting the specific guideline parameters for platelet measurement.
Conclusions:
- A standard operating procedure, implemented as a reminder system, can positively impact clinical practice, even if not fully meeting stringent prescribing guidelines.
- Unit-focused interventions can improve adherence to recommended monitoring protocols for cardiovascular medications.
- Further strategies may be needed to achieve full compliance with platelet count monitoring guidelines after GP IIb/IIIa agent administration.
Abstract:
In assessing our institution's vascular access site bleeding complication rate, we found (anecdotally) that for many patients platelet count was not measured according to recommendations of the manufacturer of the predominantly used glycoprotein (GP) IIb/IIIa agents, in either the catheterization recovery unit (CRU) or the coronary care unit (CCU). We hypothesized that a unit-focused effort to remind cardiologists to order platelet counts after percutaneous coronary interventions GP IIb/IIIa would improve compliance. Findings indicated that a greater number of patients had platelet counts drawn after a reminder effort had been implemented. For both the first and second draws, the CCU had a higher pre-reminder rate than the CRU. Post-reminder, the CCU had no significant changes, whereas the CRU showed significant increases in both the first and second draws. For post GP IIb/IIIa platelet measurement, aggregate analysis (CRU and CCU) showed that, of those patients who had platelet counts drawn pre-reminder, only 18.2% met the first guideline and only 17.1% met the second. Post-reminder results showed no significant changes for the first or second draws. We concluded that the practical application of a standard operating procedure can have a secondary beneficial effect despite not meeting the stringent parameters set in prescribing guidelines.
Related Concept Videos
Coronary Artery Disease V: Interprofessional Care
Pre-Procedural Guidelines for Assessing Blood Pressure
Peripheral Artery Disease III: Interprofessional Care
Angina V: Nursing Management
Myocarditis IV: Nursing Management
Venous Thrombosis IV: Nursing Management
