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Related Experiment Videos

Pseudotumorous pancreatitis associated with ulcerative colitis.

A Okano1, K Hajiro, H Takakuwa

  • 1Department of Gastroenterology, Tenri Hospital, Nara.

Internal Medicine (Tokyo, Japan)
|January 30, 2002
PubMed
Summary

Ulcerative colitis (UC) can uncommonly cause pancreatitis. This case highlights pseudotumorous pancreatitis as a rare extraintestinal manifestation in a UC patient, confirmed via surgical pathology.

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Area of Science:

  • Gastroenterology
  • Pathology

Background:

  • Ulcerative colitis (UC) is an inflammatory bowel disease.
  • Extraintestinal manifestations (EIMs) of UC are well-documented but uncommon.
  • Pancreatitis is a rare EIM of UC.

Observation:

  • A 66-year-old female patient with an 8-month history of UC presented with epigastric pain.
  • Elevated pancreatic enzymes were noted in laboratory examinations.
  • Imaging studies showed findings difficult to distinguish between pseudotumorous pancreatitis and pancreatic cancer.

Findings:

  • The patient underwent a distal pancreatectomy for diagnosis and treatment.
  • Histological examination revealed a tumorous lesion characterized by fibrosis and lymphocytic infiltration.
  • The case was diagnosed as pseudotumorous pancreatitis, an EIM of UC.

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Implications:

  • This case underscores the importance of considering pancreatitis, specifically pseudotumorous pancreatitis, as a rare EIM in UC patients.
  • Accurate diagnosis can be challenging, potentially requiring surgical intervention.
  • Recognizing this association may improve patient management and outcomes for UC-associated pancreatitis.