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Does cigarette smoking increase time to conception?

Marcus Munafo1, Michael Murphy, David Whiteman

  • 1Institute of Health Sciences, University of Oxford.

Journal of Biosocial Science
|January 30, 2002
PubMed
Summary
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Women who smoke cigarettes closer to conception take longer to get pregnant. Smoking cessation before attempting conception improves time to pregnancy, with weak evidence of a dose-response effect.

Area of Science:

  • Reproductive Health
  • Epidemiology
  • Behavioral Science

Background:

  • Fertility is influenced by various lifestyle factors.
  • Cigarette smoking is a known risk factor for adverse health outcomes.
  • Understanding the impact of smoking on time to conception is crucial for public health.

Purpose of the Study:

  • To investigate the relationship between cigarette smoking and time to conception.
  • To examine the influence of other health-related behaviors on fertility.
  • To assess the impact of smoking cessation timing on conception.

Main Methods:

  • Population-based sample of women from a case-control study of twinning.
  • Analysis of time to conception data based on smoking status and cessation timing.

Related Experiment Videos

  • Hierarchical regression analysis to explore dose-response relationships.

    • Main Results:

    • Women smoking close to conception had significantly longer times to pregnancy.
    • Smoking cessation prior to the year of conception was associated with shorter conception times.
    • Weak evidence suggested a dose-response relationship between cigarettes smoked and time to conception.
    • No significant association was found between other health behaviors and time to conception.

    Conclusions:

    • Continuing cigarette smoking near conception delays pregnancy.
    • Smoking cessation before attempting conception positively impacts time to pregnancy.
    • Further research may clarify the dose-response relationship in smoking and fertility.