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Thalidomide therapy for recalcitrant systemic onset juvenile rheumatoid arthritis
Thomas J A Lehman1, Kim H Striegel, Karen B Onel
1Division of Pediatric Rheumatology, Hospital for Special Surgery, Department of Pediatrics, Sanford Weill Medical Center of Cornell University, New York 10021, USA.
The Journal of Pediatrics
|January 30, 2002
Abstract:
Systemic onset juvenile rheumatoid arthritis unresponsive to nonsteroidal anti-inflammatory drugs may be controlled with corticosteroids, but these drugs have significant side effects. We report 2 steroid-dependent children with systemic onset juvenile rheumatoid arthritis who did not respond to multiple nonsteroidal anti-inflammatory drugs, methotrexate, azathioprine, cyclosporine, and etanercept. Both children had significant improvement with thalidomide therapy.