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Updated: Aug 10, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
[Malignant melanoma of the penis]
V J Bañón Pérez1, G Server Pastor, P Valdelvira Nadal
1Servicio de Urología H.U. Virgen de la Arrixaca Crta. Madrid-Cartagena s.n. C.P.: 30120 El Palmar, Murcia, España.
Objective:
To report a case of malignant melanoma of the penis, a rare malignant neoplasm whose aggressive behaviour carries a poor prognosis.
Methods:
A 58-year-old male consulted for a pigmented elevated lesion in the balanopreputial sulcus. The biopsy was positive for melanoma. Complementary studies did not demonstrate disseminated disease.
Results:
Partial resection of the penis and bilateral inguinal lymphadenectomy were performed. Histological analysis showed two positive nodes in the same lymphatic chain. Interferon was administered for 6 months. The patient remains disease-free at 35 months' follow-up.
Conclusions:
Although surgery is the treatment of choice, adjuvant therapy (chemotherapy and immunotherapy) should be considered in those patients without localized disease.
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