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[Osteoporosis in the man].

H Resch1, E Gollob, S Kudlacek

  • 1II. Medizinische Abteilung, Krankenhaus der Barmherzigen Schwestern, Stumpergasse 13, A-1060 Wien. med2.wien@bhs.at

Wiener Medizinische Wochenschrift (1946)
|January 31, 2002
PubMed
Summary

Osteoporosis in men, often secondary to conditions like hypogonadism, is underrecognized. Aminobisphosphonates are favored for treating male osteoporosis, including idiopathic and glucocorticoid-induced cases.

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Area of Science:

  • Endocrinology
  • Bone Metabolism
  • Geriatric Medicine

Context:

  • Osteoporosis in men is a significant health concern, with a 25% lifetime risk of low trauma fracture by age 60.
  • Men account for approximately one-third of all hip fractures.
  • Unlike postmenopausal osteoporosis, male osteoporosis is often secondary to underlying conditions.

Purpose:

  • To review the prevalence, causes, and treatment of osteoporosis in men.
  • To highlight the role of hypogonadism and glucocorticoid use in male osteoporosis.
  • To discuss current and potential therapeutic strategies for male osteoporosis.

Summary:

  • Male osteoporosis is frequently secondary, linked to hypogonadism or long-term glucocorticoid therapy in about 50% of cases.
  • Low serum estradiol and elevated sex hormone-binding globulin may contribute to idiopathic male osteoporosis.
  • Treatment options include calcium, vitamin D, testosterone, and various medications like bisphosphonates.

Impact:

  • Current evidence supports aminobisphosphonates as a preferred treatment for idiopathic and glucocorticoid-induced osteoporosis in men.
  • Improved understanding and management of male osteoporosis can reduce fracture risk and improve patient outcomes.
  • Further research into the pathogenesis and treatment of male osteoporosis is warranted.

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