Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Interindividual variability of contingent negative variation].

M Crasson1, M Lembreghts, A el Ahmadi

  • 1Université de Liège, unité de psychoneuroendocrinologie, B-35, CHU, 4000 Liège, Belgique. mcrasson@ulg.ac.be

Neurophysiologie Clinique = Clinical Neurophysiology
|January 31, 2002
PubMed
Summary

This study investigated the Contingent Negative Variation (CNV) in relation to age, gender, and psychological factors. Results show these factors significantly influence CNV amplitude and distribution, impacting clinical applications.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Third nerve schwannoma mimicking recurrent painful ophthalmoplegic neuropathy.

Journal francais d'ophtalmologie·2024
Same author

Reduced Balance Restoration Capacities Following Unilateral Vestibular Insult in Elderly Mice.

Frontiers in neurology·2018
Same author

Age-Related Impairment of Hand Movement Perception Based on Muscle Proprioception and Touch.

Neuroscience·2018
Same author

Additional intranasal oxytocin to escitalopram improves depressive symptoms in resistant depression: an open trial.

European psychiatry : the journal of the Association of European Psychiatrists·2014
Same author

Ascending aortic aneurysm in a patient with mixed gonadal dysgenesis.

Annales d'endocrinologie·2010
Same author

Erectile dysfonction, a sentinel of cardiovascular disease...a symptom not to be neglected.

Acta chirurgica Belgica·2010

Area of Science:

  • Neuroscience
  • Cognitive Electrophysiology
  • Psychophysiology

Background:

  • Standardized protocols, normative data, and variability are crucial for clinical use of Contingent Negative Variation (CNV).
  • Understanding factors influencing CNV is essential for accurate interpretation in clinical settings.

Purpose of the Study:

  • To investigate the influence of age, gender, and psychological factors on CNV.
  • To analyze CNV amplitude, morphology, and topographic distribution in relation to performance and variability.
  • To examine the effect of inter-stimulation intervals on CNV recordings.

Main Methods:

  • Recorded CNV in 86 healthy control subjects (44 male, 42 female) during a reaction time paradigm.
  • Analyzed CNV characteristics including amplitude, morphology, and topography.

Related Experiment Videos

  • Assessed the impact of age, gender, stress, and anxiety on CNV, alongside reaction times and P300.
  • Compared CNV recordings with 1-second and 3-second inter-stimulation intervals in a subset of 12 subjects.

    • Main Results:

    • CNV amplitude (M1, M2) increased and shifted to more central sites with age.
    • Men exhibited faster reaction times and lower post-S1 P300 compared to women.
    • Increased life events-related stress and current anxiety levels correlated with decreased CNV amplitude.

    Conclusions:

    • Age, gender, and psychological factors significantly contribute to CNV variability.
    • These findings highlight the importance of considering individual differences for standardized CNV application in clinical practice.
    • CNV is a sensitive measure influenced by demographic and psychological states.