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Transcriptional control: an activating role for arginine methylation
Judith K Davie1, Sharon Y R Dent
1Department of Biochemistry and Molecular Biology, U.T. M.D. Anderson Cancer Center, Houston, Texas 77030, USA.
Current Biology : CB
|January 31, 2002
Abstract:
A rare histone modification, arginine methylation, has been linked to activation of hormone-responsive genes. Interestingly, methylation of a lysine residue in the same histone is present prior to hormone activation, but is excluded from the active loci.