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Related Experiment Videos

Screening for tuberculosis among orphans in a developing country.

Judith Francis1, Alison Reed, Fitsum Yohannes

  • 1School of Medicine, University of Miami, Miami, FL 33101, USA.

American Journal of Preventive Medicine
|January 31, 2002
PubMed
Summary

Tuberculosis (TB) is a significant concern in Haiti. This study found TB prevalence in orphans to be 1123 per 100,000, highlighting them as a high-risk group needing targeted screening.

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Area of Science:

  • Public Health
  • Infectious Diseases
  • Pediatrics

Background:

  • Tuberculosis (TB) poses a global health challenge, with Haiti experiencing a high prevalence.
  • While TB screening is recommended in congregate settings, institutional orphanages are often overlooked.
  • Haiti reports a TB prevalence of 123.9 per 100,000 population.

Purpose of the Study:

  • To assess the prevalence of tuberculosis infection among orphans in Haiti.
  • To identify if children in orphanages represent a previously unrecognized high-risk group for TB.

Main Methods:

  • Screened 445 orphans across six Haitian orphanages using the purified protein derivative (PPD) tuberculin test.
  • Recorded induration >5 mm at 48-72 hours as a positive PPD test.
  • Defined active TB cases by specific symptoms and signs of extrapulmonary TB.

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Main Results:

  • 170 out of 445 orphans (38,202 per 100,000) tested positive for TB infection.
  • Ten active TB cases were identified among the screened population.
  • Orphanages with active cases showed 44% tuberculin positivity, versus 13% in those without active cases.

Conclusions:

  • The prevalence of TB infection among screened orphans was 1123 per 100,000, significantly higher than the general Haitian population.
  • Children residing in orphanages should be considered a high-risk group for TB infection.
  • Further research on TB in orphans in developing countries is warranted.