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How to write an evidence-based clinical review article.

Jay Siwek1, Margaret L Gourlay, David C Slawson

  • 1Department of Family Medicine, Georgetown University Medical Center, Washington, DC 20007, USA. afp@family.georgetown.edu

American Family Physician
|February 1, 2002
PubMed
Summary

This guide outlines how to write evidence-based clinical review articles for family physicians. It details structuring content, conducting literature searches, and rating evidence levels for clinical recommendations.

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Area of Science:

  • Medical Writing
  • Evidence-Based Medicine
  • Family Practice

Background:

  • Clinical review articles (updates) differ from systematic reviews and meta-analyses.
  • Updates offer broad topic discussions, while systematic reviews synthesize comprehensive literature.
  • Meta-analyses use statistical analysis for focused clinical questions.

Purpose of the Study:

  • Provide guidelines for writing evidence-based clinical review articles for American Family Physician.
  • Ensure relevance to family practice and common clinical interests.
  • Standardize the structure and content of review articles.

Main Methods:

  • Select topics of common interest and relevance to family practice.
  • Include continuing medical education objectives and details of literature search methodology.

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  • Utilize evidence-based review sources (e.g., Cochrane Collaboration, Clinical Evidence).

    • Main Results:

    • Emphasize evidence based on clinical outcomes (morbidity, mortality, quality of life).
    • Prioritize studies from primary care populations.
    • Rate key recommendations using a defined evidence level scale (A, B, C).

    Conclusions:

    • Adherence to these guidelines will produce high-quality, evidence-based clinical reviews.
    • Standardized reviews enhance the utility of medical literature for family physicians.
    • Clear evidence rating aids in the application of recommendations in clinical practice.