[Histomorphological study of wound regeneration in animals irradiated for a long time with low-intensity microwaves]

Experimental study on 80 guinea pigs showed that in the animals exposed for a long time to the action of microwabes of low intensity the linear skin wounds healed by primary intension much more rapidly than in the non-irradiated animals. The postoperative scar was much more reliable in the irradiated animals. On the third day the irradiated animals were found to have a more intensive regeneration of the epithelium in the inflicted wound, and an intensive development of the granular tissue in the inferior portions. Later, an aceelerated synthesis of proteins, including that of collagen in the wound was observed; there was also a marked process of maturation of the granular tissue and formation of the intercellular substance. On the 7th-9th days fresh connective tissue (rich in fibroblasts with young fuchsinophilous collagen fibers) replaced the granular tissue; it was more mature than in the non-irradiated animals.