[Coordination centers for clinical studies--structure and integration of non-university hospitals]

The Integration of non-university hospitals in clinical trials is absolutely necessary to ensure patient availability and generalisation. In our survey we observed significant problems with the conduction of clinical trials in non-university hospitals. Important aspects of these problems are caused by the lack of infrastructure and personnel as well as by rising standards for clinical conduction. The establishment of Coordination Centres for Clinical Trials (KKS) has significantly improved the ability to support clinical trials in non-university hospitals in the future.