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Bone marrow necrosis and refractory HELLP syndrome in a patient with catastrophic antiphospholipid antibody syndrome
Jayashree Sinha1, Iftikhar Chowdhry, Sarah Sedan
1Albert Einstein College of Medicine and White Plains Medical Center Bronx New York, USA.
The Journal of Rheumatology
|February 5, 2002
Abstract:
We describe a 22-year-old woman who developed extensive and fatal bone marrow necrosis along with involvement of liver, lung, and central nervous system during pregnancy in the background of very high titers of antiphospholipid and anti-beta2 glycoprotein antibodies. This case illustrates a rarely recognized, potentially fatal complication of aPL in the setting of pregnancy.