Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pre-eclampsia, diagnosis and treatment.

G V Sunanda1, R Johanson

  • 1Academic Department of Obstetrics and Gynaecology, North Staffordshire Hospital Trust, Maternity Building, Newcastle Road, Stoke On Trent, ST4 6QG, UK.

Expert Opinion on Pharmacotherapy
|February 5, 2002
PubMed
Summary

Pre-eclampsia, a pregnancy disorder with high blood pressure, lacks understood causes. Research explores abnormal placentation, predictive tests, and potential preventions like magnesium sulfate.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Enterouterine fistula: a rare and unusual complication of uterine artery embolisation.

Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology·2011
Same author

Sulphur distributions, with special reference to the cystine plus cysteine and methionine contents, of the seeds and seed proteins of two varieties of soya beans.

The Australian journal of experimental biology and medical science·2010
Same author

Disseminated extra pulmonary tuberculosis in an immune competent pregnant woman.

Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology·2009
Same author

A case of triploidy.

Fertility and sterility·2005
Same author

Operative vaginal delivery rates in the United Kingdom.

Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology·2004
Same author

Critical appraisal workshops to promote evidence-based healthcare.

Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology·2004

Area of Science:

  • Obstetrics and Gynecology
  • Maternal-Fetal Medicine
  • Pathophysiology of Pregnancy Disorders

Background:

  • Pre-eclampsia is a complex multisystem disorder unique to pregnancy.
  • Characterized by hypertension and proteinuria, its exact pathogenesis remains elusive despite extensive research.
  • Abnormal placentation, potentially involving immune factors and placental maladaptation, is hypothesized as an early trigger.

Purpose of the Study:

  • To review the current understanding of pre-eclampsia pathogenesis.
  • To discuss existing and novel diagnostic and predictive methods.
  • To explore prophylactic and therapeutic strategies for pre-eclampsia and eclampsia.

Main Methods:

  • Literature review of pre-eclampsia research.
  • Analysis of risk factors and diagnostic innovations (e.g., uterine artery Doppler).
  • Evaluation of prophylactic agents (e.g., antiplatelet agents, calcium, vitamins C and E) and therapeutic approaches.

Main Results:

  • No single test currently meets standard diagnostic criteria for pre-eclampsia.
  • Several interventions show potential prophylactic value.
  • The MAGPIE trial investigates magnesium sulfate for eclampsia prevention.
  • Management strategies focus on preventing hypertensive injury and timely delivery.

Conclusions:

  • Understanding pre-eclampsia pathogenesis requires further investigation.
  • Continued research into specific antihypertensive agents and conservative management is essential.
  • Predictive testing and prophylactic measures need further validation and refinement.

Related Experiment Videos