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Updated: Aug 3, 2026
Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
Published on: April 11, 2018
[Treatment and prognosis of 33 patients with recurrent retroperitoneal soft tissue sarcomas]
Objective:
To investigate the treatment and the prognosis of patients with recurrent retroperitoneal soft tissue sarcomas.
Method:
The clinical data of 33 patients, treated for recurrent retroperitoneal soft tissue sarcomas from 1972 to 1996 were analyzed retrospectively.
Result:
Complete tumor resection was performed for 17 patients (51.5%) with tumor recurrence for the first time. 2, 3, 1 patients underwent multiple organs resection respectively when the sarcoma relapsed initially, secondly and thirdly. Fourteen patients were given adjuvant radiotherapy and chemotherapy postoperatively. Twenty-nine patients were followed for up for 6 to 12 months. Fifteen (51.7%) of them died. Seven of them survived beyond 5 years and 2 over 10 years. The 1-, 3-, and 5-years survival rate was 85.7%, 54.9% and 42.3% respectively.
Conclusion:
Surgery is effective in improving the survival rate of patients with recurrent retroperitoneal soft tissue sarcomas, including those with repeatedly recurrent sarcomas. Multiple organ resection could be beneficial to the curative resection rate. Adjuvant radiotherapy and chemotherapy might improve the local control of relapsed sarcomas to some extent.
