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Updated: Jul 10, 2026

Membrane Remodeling of Giant Vesicles in Response to Localized Calcium Ion Gradients
Published on: July 16, 2018
Precipitation membrane effects in biologic membranes: the role of calcium
Abstract:
Biologic membranes display rectification of electrical current, as well as other properties, in many respects similar to precipitation membranes. The experiments reported here, performed in frog skin, show that these characteristics are dependent upon the presence of calcium. Upon elimination of calcium from the bathing solution, the property of electrical rectification is lost, the current-voltage relation assuming a linear form. Readministration of calcium brings about complete recovery of the rectification pattern. This behavior is analogous to chemical deconditioning of precipitation membranes. Our findings support the assumption that the binding of calcium in biologic membranes produces electrical effects characteristic of precipitation membranes.
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