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[Aranoza -- a new Russian antineoplastic drug]
V A Gorbunova1, N F Orel, O V Semina
1N.N. Blokhin Center for Oncology Research, Russian Academy of Medical Sciences, Moscow.
Voprosy Onkologii
|February 6, 2002
Abstract:
Myelosuppression is a toxicity-related limitation for aranoza dosage. The drug proved effective in the treatment of uterine sarcoma, cancer of the head and neck, breast, Hodgkin's disease and lymphosarcoma during stage II of clinical studies. Complete regression was reported in the treatment of melanoma (ca. 12%). Good results of chemoimmunotherapy should be expected in untreated patients as well as intraarterial infusions for local lesions of the extremities. Clinical trials of aranoza used in combined modalities of therapy in various sites continue.