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Updated: Jul 21, 2026

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Protocol for Dengue Infections in Mosquitoes (A. aegypti) and Infection Phenotype Determination
Published on: July 4, 2007
[Hemorrhagic dengue in primary dengue]
H Palacios Serrano1, M E Vargas Caballero, T M Aguirre Portuondo
1Hospital Infantil Sur Docente, Santiago de Cuba.
Revista Cubana De Medicina Tropical
|February 6, 2002
Summary
This case study details a 7-year-old boy with hemorrhagic dengue during a 1997 epidemic. Despite rare occurrence and no prior history, he recovered fully from severe symptoms including shock and sepsis.
Area of Science:
- Virology
- Pediatrics
- Epidemiology
Background:
- Dengue hemorrhagic fever (DHF) is a severe form of dengue fever.
- The 1997 dengue epidemic in Santiago de Cuba saw 77 pediatric cases.
- Dengue virus had not circulated in the region for over 15 years prior to this epidemic.
Observation:
- A 7-year-old boy presented with symptoms of hemorrhagic dengue.
- He developed shock, hemoconcentration, effusions, and thrombocytopenia on the fourth day.
- The patient also developed a nosocomial sepsis during hospitalization.
Findings:
- This was the sole case of hemorrhagic dengue identified among pediatric patients during the epidemic.
- The patient had no prior history of dengue or related diseases.
- Despite the severity and unusual circumstances, the boy achieved a complete recovery within 20 days.
Implications:
- This case highlights the potential for severe dengue manifestations even in the absence of prior exposure or recent viral circulation.
- It underscores the importance of vigilant clinical monitoring and prompt management in pediatric dengue cases.
- The successful recovery emphasizes the effectiveness of supportive care in managing critical dengue complications.
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