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Updated: Aug 2, 2026

A Co-culture Method to Investigate the Crosstalk Between X-ray Irradiated Caco-2 Cells and PBMC
Published on: January 30, 2018
The effects of therapeutic radiation on colonic mucosa
Abstract:
Low to moderate doses of therapeutic irradiation are capable of producing bizarre cytologic changes in the mucosal cells of colorectal crypts. This may be associated with eosinophilia of the lamina propria and with eosinophilic crypt abscesses. The bizarre cells generally line intact crypts and do not exhibit invasive behavior. The change subsides within 1-2 months at the dose levels studied (approximately 2000 rads).
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Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease II: Ulcerative Colitis

