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Laryngeal gout.

A Tsikoudas1, A P Coatesworth, D P Martin-Hirsch

  • 1Department of Otolaryngology, Hull Royal Infirmary, Hull, UK. atsikoudas@yahoo.com

The Journal of Laryngology and Otology
|February 6, 2002
PubMed
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Laryngeal gout is rare, with only 12 cases previously reported. This study details three new cases, highlighting acute and chronic presentations and emphasizing the need for clinical awareness in gout patients with laryngeal symptoms.

Area of Science:

  • Otolaryngology
  • Rheumatology
  • Pathology

Background:

  • Laryngeal gout is an exceptionally rare condition, with limited documented cases in medical literature.
  • Clinical awareness of laryngeal involvement in gout patients may be suboptimal, contributing to underdiagnosis.

Observation:

  • This series presents three new cases of laryngeal gout, the largest reported cohort to date.
  • Includes a novel case of acute gouty cricoarytenoiditis causing airway compromise requiring tracheotomy.
  • Details two cases of chronic tophaceous infiltration of the thyroid lamina, visualized with computed tomography (CT).

Findings:

  • Gout can manifest in the larynx, presenting as acute airway obstruction or chronic tophaceous deposits.
  • Symptoms such as hoarseness, odynophagia, dysphagia, stridor, or neck lumps in gout patients warrant consideration of laryngeal gout.

Related Experiment Videos

  • Computed tomography (CT) can aid in diagnosing chronic tophaceous involvement of the laryngeal structures.

    • Implications:

    • Increased clinical suspicion for laryngeal gout is crucial in patients with a history of gout presenting with relevant laryngeal symptoms.
    • Management strategies vary from tracheotomy for acute airway compromise to endoscopic procedures or permanent tracheostomy for chronic issues.
    • Further research and case reporting are needed to better understand the prevalence and optimal management of this rare condition.