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Published on: February 17, 2023
[Acute Gastroenteritis in hospitalized children. 14-Year evolution]
C Alcalde Martín1, L Gómez López, M I Carrascal Arranz
1Servicio de Pediatría, Hospital Universitario Río Hortega, Valladolid, Spain.
Insights
This study analyzed pediatric acute gastroenteritis, finding rotaviruses most common. Bacterial gastroenteritis, marked by fever and bloody stools, was distinguished from viral causes.
Area of Science:
- Pediatric infectious diseases
- Microbiology
- Clinical epidemiology
Context:
- Acute gastroenteritis is a significant cause of pediatric hospitalization.
- Understanding the etiological agents and clinical presentations is crucial for effective management.
- Longitudinal data provides insights into trends and differences in disease patterns.
Purpose:
- To analyze the etiology and clinical evolution of acute gastroenteritis in hospitalized children.
- To differentiate between viral and bacterial gastroenteritis based on clinical and laboratory findings.
- To identify trends in hospital admissions for specific enteropathogens over time.
Summary:
- Rotaviruses were the most frequent cause of acute gastroenteritis in hospitalized children (46.5%).
- Bacterial gastroenteritis, caused by Salmonella, E. coli, and Shigella, showed distinct clinical features including hyperthermia and fecal blood.
- Hospital admissions for Salmonella, E. coli, Shigella, and adenoviruses significantly decreased during the study period (1987-2000).
Impact:
- Identifies key clinical indicators (fever, bloody stools) for distinguishing bacterial from viral gastroenteritis in children.
- Highlights the declining incidence of certain bacterial and viral pathogens, potentially due to public health interventions.
- Provides valuable etiological and epidemiological data for pediatric infectious disease research and clinical practice.
Objectives:
To analyze the etiology and evolution of patients with acute gastroenteritis hospitalized in our pediatric department and to study the clinical and laboratory differences between acute viral and bacterial gastroenteritis.
Patients And Methods:
We studied the children with a diagnosis of acute gastroenteritis, aged between 0 and 14 years, who were consecutively admitted between 1987 and 2000. Differences were considered statistically significant if p < 0.05.
Results:
A total of 2,613 patients diagnosed with acute gastroenteritis were hospitalized (10.4 % of hospital admissions). The most common pathogens isolated were rotaviruses (46.5 %), followed by Salmonella (32.6 %) and Campylobacter (19.3 %). Hospital admissions due to Salmonella (p < 0.0001), other bacteria (Escherichia coli and Shigella) (p < 0.002) and adenoviruses (p < 0.01) significantly decreased. Rotaviruses were the most frequently detected pathogens in winter and in children aged less than 1 year (p < 0.0001). The incidence of Salmonella spp was greater in summer and in children older than 2 years (p < 0.0001). The incidence of hyperthermia (rectal temperature higher than 38.5 degreeC) (p < 0.0001), dehydration (p < 0.0005) and fecal blood (p < 0.0001) was higher in bacterial diarrheas. Erythrocyte sedimentation rate (p < 0.001) and leukocyte counts were higher in bacterial gastroenteritis (p < 0.01).
Conclusions:
Rotaviruses were the most frequently isolated enteropathogens. The features that best distinguished between bacterial and viral diarrhea were hyperthermia and fecal blood. Hospital admissions due to Salmonella Shigella E. coli, and adenoviruses significantly decreased.
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