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Clinical and functional target validation using tissue and cell microarrays
Spyro Mousses1, Anne Kallioniemi, Päivikki Kauraniemi
1Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892-8000, USA.
Current Opinion in Chemical Biology
|February 6, 2002
Abstract:
Expression levels of thousands of genes or proteins can be readily determined using microarray techniques. However, this represents only the first step in understanding the biological and medical significance of these molecules. New high-throughput techniques, such as tissue and cell microarrays, will facilitate clinical and functional analysis of molecular targets.