Related Experiment Video
Updated: Jul 14, 2026

Production and Purification of Non Replicative Canine Adenovirus Type 2 Derived Vectors
Published on: December 3, 2013
Abstract:
VA-RNA from adenovirus 2 (Ad2) infected cells is shown to consist of two species. The gene coding for the major species maps at position 30 on the viral DNA, where it spans a site cleaved by the restriction enzyme Bam Hl. The minor species, constituting a few percent of the total VA-RNA, is distantly related in oligonucleotide composition to the major species. Its template maps within 700 base pairs to the right of the gene for the major species. The direction of transcription is from left to right on the conventional Ad2 map. These results, gained with a novel method for blotting (E. M. Southern, manuscript in preparation), have also led to the identification of the Bam Hl recognition sequence.
More Related Videos
13:36Utilizing the Antigen Capsid-Incorporation Strategy for the Development of Adenovirus Serotype 5-Vectored Vaccine Approaches
Published on: May 6, 2015
08:14Combined Genetic and Chemical Capsid Modifications of Adenovirus-Based Gene Transfer Vectors for Shielding and Targeting
Published on: October 26, 2018
Related Concept Videos
Leaky Scanning
Rous Sarcoma Virus (RSV) and Cancer
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
Viruses with RNA Genomes
Respiratory Syncytial Virus Disease