[A guide line for antibiotic therapy of infectious diseases of the central nervous system]
Related Experiment Video
Updated: Sep 16, 2026

Systemic and Local Drug Delivery for Treating Diseases of the Central Nervous System in Rodent Models
Published on: August 17, 2010
1Department of Neurosurgery, Neurological Institute, Tokyo Women's Medical University, Tokyo, Japan.
Abstract:
The purpose of this paper is to provide assistance to clinicians in the treatment of infectious diseases of the central nervous system. Antibiotic therapy should be initiated as soon as the diagnosis is made and should not be delayed until the next scheduled dose or until investigations have been performed. The infecting organism is usually unknown when treatment is initiated and often remains so, and therefore empirical therapy should always cover the most common suspected organisms. The choice of antibiotics, dosage, and route of administration depends upon the severity of illness. Likely pathogens and the known sensitivities of pathogens of the central nervous system are discussed.
Related Concept Videos
Bacterial Meningitis
Cryptococcal Meningitis
Bacterial Meningitis I: Introduction
Bacterial Meningitis II: Pathophysiology
Encephalitis ll: Pathophysiology
Brain Abscess l: Introduction

