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Updated: Aug 19, 2026

A Simple and Efficient Method to Isolate Macrophages from Mixed Primary Cultures of Adult Liver Cells
Published on: May 24, 2011
Are they microcytes or macrocytes? Can we do a better job?
Daniel E Haun1, Argie Leach, Rita Vivero
1Department of Pathology, Medical Center of Louisiana at New Orleans, USA.
Abstract:
As an attempt to improve accuracy in the grading of microcytes and macrocytes, a custom reticle was developed and evaluated. The evaluation looked at grading accuracy, reproducibility, speed, and opinion. In this study, the reticle improved the grading accuracy and reproducibility of graders who were "poorer performers." The reticle offered no advantage to the speed of the evaluation. The opinion survey indicated improved confidence with the reticle, and most of the participants found the device useful. The improvement to "poorer performers" is sufficient to warrant use in actual practice.

