Related Experiment Video
Updated: Oct 2, 2026
Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
[Early results of 1,110 cases of coronary artery bypass]
Insights
Coronary artery bypass surgery in 1110 patients demonstrated a low early mortality rate of 0.81%. Successful outcomes highlight the importance of complete revascularization and meticulous perioperative care in coronary artery bypass grafting.
Area of Science:
- Cardiovascular Surgery
- Cardiac Surgery Outcomes
- Myocardial Revascularization
Context:
- Experience with 1110 coronary artery bypass (CAB) procedures performed between January 1996 and March 1999.
- Patient cohort included diverse demographics and comorbidities such as myocardial infarction, unstable/stable angina, left main trunk stenosis, and reduced ejection fraction.
Purpose:
- To present the surgical experience and outcomes of coronary artery bypass grafting.
- To evaluate the efficacy and safety of CAB in a large patient cohort.
Summary:
- 1110 patients underwent CAB, with 1048 on cardiopulmonary bypass (CPB) and 60 on beating heart.
- Grafting strategies included single to multiple grafts using internal mammary artery, saphenous vein, and radial artery conduits.
- Concomitant procedures involved ventricular aneurysm repair, valvular surgery, and septal rupture repair.
Impact:
- Achieved a low early mortality of 0.81% (9 deaths), with uneventful discharge for 1101 patients.
- Identified key complications including low cardiac output, need for intra-aortic balloon pump, perioperative myocardial infarction, and bleeding requiring rethoractomy.
- Emphasizes that complete revascularization and optimal perioperative management are crucial for successful coronary artery bypass outcomes.
Objective:
To introduce our experience with Coronary artery bypass.
Methods:
From January 1996 to March 1999, coronary artery bypass was in 1110 patients at our hospital. They were 985 men and 125 women, aged 27 - 78 years (57 +/- 9). 500 patients were aged over 60 years. 670 patients had a history of myocardial infarction. 450 patients suffered from instable, and 460 from stable angina. 169 patients had stenosis of the left main trunk (>or= 50%). The heart function of 240 patients was over NYHA class III, the EF of 123 patients was less than 40%. 454 patients were associated with hypertension, 133 with diabetes, 131 with ventricular aneurysm, 48 with valvular disease, and 5 with rupture of ventricular septal. 1048 procedures were performed on hypothermia cardiopulmonary bypass (CPB) and 60 on beating heart. Myocardial preservation was carried out by cold blood cardioplegia with potassium. The average time of CPB was 115 +/- 35 minutes, and that of aortic cross clamp was 72 +/- 24 minutes 110 cases received one graft, 145 cases two grafts, 415 cases three grafts, and 439 cases four and more than four grafts. Left internal mammary artery, great saphenous vein, and radial artery were used as coronary artery bypass conduits on 751, 877 and 101 patients, respectively. Total arterial myocardial revascularization was performed on 72 patients. Concomitant operation included ventricular aneurysmetomy (112 cases), plication (14), left ventriculoplasty (5), valvular procedures (48), repair ventricular septal rupture (5).
Results:
1 101 patients were discharged uneventfully. Early death occurred in 9 patients, (0.81%). Complication included low cardiac output (11 cases), introaortic balloon pump (7), perioperative myocardial infarction (2), complication of brain (3), and rethoractomy for bleeding (4).
Conclusions:
To identify adequate target vessel and completely revascularize ischemic myocardium are the key of coronary artery bypass. Perioperative treatment is important.
