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[Effect of escharectomy during burn shock stage on stress response]
Objective:
To investigate changes in hormones of plasma and the effect of escharectomy during burn shock stage on early stress response after burn.
Methods:
Sixteen male minipigs were subjected to a 35% TBSA III degree burn injury. The burned minipigs were randomly divided into two groups: escharectomy during burn shock stage group (S group) and escharectomy group after burn shock stage (N group). The sequential changes in plasma levels of insulin, glucagon, cortisol, GH, IGF-I, albumin were analyzed.
Results:
The serum concentration of insulin, glucagon, cortisol increased to some degree, whereas the serum concentration of GH, IGF-I decreased obviously after burn. As compared with the N group, no significant difference in the serum concentration of glucagon, cortisol, GH, IGF-I, was observed.
Conclusions:
Escharectomy during burn shock stage could not aggravate stress response after burn.