Deep vein thrombosis and pulmonary embolism in the Chinese population

P L Nandi1, W S Li, R Leung

  • 1Department of Surgery, The University of Hong Kong Medical Centre, Queen Mary Hospital, Pokfulam, Hong Kong.

Insights

Deep vein thrombosis (DVT) and pulmonary embolism (PE) are increasing in Chinese patients, contrary to past beliefs. Prophylaxis is recommended for high-risk Chinese individuals to prevent these serious conditions.

Area of Science:

  • Vascular Medicine
  • Public Health
  • Epidemiology

Background:

  • Deep vein thrombosis (DVT) and pulmonary embolism (PE) are significant health concerns in Western populations.
  • A common misconception suggests DVT is rare in Asian populations, including the Chinese.
  • Emerging evidence indicates a rising incidence of venous thromboembolism (VTE) in Chinese patients.

Purpose of the Study:

  • To review the current literature on the incidence of DVT and PE in Chinese patients.
  • To evaluate the effectiveness of prophylaxis in reducing VTE events in this demographic.
  • To inform clinical practice regarding VTE prevention in at-risk Chinese populations.

Main Methods:

  • Literature review of studies on venous thromboembolism in Chinese patients.
  • Analysis of reported incidence rates of DVT and PE.
  • Evaluation of prophylaxis efficacy data from relevant clinical trials and observational studies.

Main Results:

  • The incidence of DVT and PE appears to be increasing among Chinese patients.
  • Prophylaxis has demonstrated significant efficacy, reducing DVT incidence by 66% and PE by 50% in studies.
  • High-risk Chinese patients benefit substantially from prophylactic measures.

Conclusions:

  • The belief that DVT is rare in Chinese populations is being challenged by increasing incidence rates.
  • Prophylaxis is a crucial intervention for preventing DVT and PE in high-risk Chinese patients.
  • Further research and clinical attention are warranted for VTE management in this growing patient group.

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