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Published on: July 18, 2014
Severe hypocalcemia: a rare cause of reversible heart failure
N Mikhail1, A El-Bialy, J Grosser
1Department of Medicine, Endocrinology Division, Olive View-UCLA Medical Center, Sylmar, CA 91342.
Insights
Severe hypocalcemia can cause heart failure, but it is reversible with calcium correction. This case highlights the importance of checking calcium and magnesium levels in heart failure patients.
Area of Science:
- Cardiology
- Endocrinology
- Internal Medicine
Background:
- Calcium is vital for myocardial contractility.
- Hypocalcemia is an underrecognized cause of heart failure.
- Hypoparathyroidism can lead to severe hypocalcemia.
Purpose of the Study:
- To report a case of hypocalcemic heart failure.
- To emphasize the reversibility of hypocalcemic heart failure.
- To recommend screening for hypocalcemia in heart failure patients.
Main Methods:
- Case report of a patient with idiopathic hypoparathyroidism.
- Management of severe hypocalcemia and hypomagnesemia.
- Clinical assessment of heart failure symptoms and plasma calcium levels.
Main Results:
- The patient presented with congestive heart failure.
- Heart failure symptoms significantly improved with calcium level correction.
- This suggests a direct link between hypocalcemia and heart failure.
Conclusions:
- Hypocalcemic heart failure is a reversible condition.
- Plasma calcium measurement is crucial in heart failure work-up.
- Magnesium levels should also be assessed and corrected in hypocalcemic patients.
Abstract:
Despite the crucial role of calcium in myocardial contractility, hypocalcemia has been rarely reported as a cause of heart failure. In this article, the authors describe a case of severe hypocalcemia caused by idiopathic hypoparathyroidism and worsened by concomitant hypomagnesemia. The patient presented with congestive heart failure that improved dramatically with amelioration of plasma calcium levels. This case and other similar cases in the literature revealed that hypocalcemic heart failure is reversible. Measurement of plasma calcium should be included in the initial work-up of all patients with heart failure, and plasma magnesium must also be checked and corrected if hypocalcemia is demonstrated. (c)2001 CHF, Inc.
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