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"Amalgam disease"--poisoning, allergy, or psychic disorder?
B Gottwald1, I Traenckner, J Kupfer
1Department of Medical Psychology, University of Giessen, Germany.
International Journal of Hygiene and Environmental Health
|February 9, 2002
Summary
Toxic exposure from amalgam fillings is unlikely to cause "amalgam disease." Patients often have atopic predisposition and psychological factors like depression, suggesting these require focus over mercury toxicity.
Area of Science:
- Environmental Health
- Toxicology
- Allergology
- Psychology
Background:
- Patients frequently attribute health complaints to amalgam fillings.
- However, a direct link between toxic exposure and symptoms is often unclear.
Purpose of the Study:
- To investigate toxicological, allergological, and psychological factors in patients with amalgam-associated complaints.
- To compare these parameters with a matched control group.
Main Methods:
- Analysis of mercury levels in blood, saliva, and urine.
- Assessment of atopic predisposition, IgE levels, and patch testing for amalgam/metal sensitivity.
- Psychometric evaluation including depression and somatization disorder screening.
Main Results:
- Similar mercury concentrations were found in patients and controls.
- Atopic predisposition was significantly higher in patients (11/40 vs. 5/40).
- Patients reported increased psychic strain and depression; somatization disorders were more prevalent.
Conclusions:
- Toxic mercury exposure is not a significant factor in "amalgam disease."
- Atopy and psychological factors, particularly depression, are more relevant.
- Treatment should prioritize allergological and psychological interventions.