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Related Concept Videos

The Arch of Aorta01:10

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Related Experiment Video

Updated: Jul 27, 2026

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
14:58

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

Published on: October 20, 2017

Aortic arch replacement for recurrent cerebral embolization.

Gilead Lancaster1, Constantinos J Lovoulos, Michael Moussouttas

  • 1Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06510, USA.

The Annals of Thoracic Surgery
|February 9, 2002
PubMed
Summary

Surgical removal of aortic arch atheromas effectively stopped recurrent embolic strokes in a patient. This aortic arch repair offers a promising solution for preventing future cerebral vascular accidents.

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Area of Science:

  • Cardiovascular Surgery
  • Neurology
  • Vascular Medicine

Background:

  • Aortic arch atheromas are a potential source of cerebral emboli, leading to ischemic strokes.
  • The surgical management of aortic arch atheromas remains controversial due to associated risks.
  • Cerebral vascular accidents (CVAs) can result from atheromatous embolization from the aortic arch.

Observation:

  • A 58-year-old woman experienced recurrent CVAs attributed to large, mobile atheromas in the aortic arch and descending thoracic aorta.
  • Despite anticoagulation with warfarin (Coumadin) and aspirin, cerebrovascular events persisted, and atheromas grew.
  • Transcranial ultrasound confirmed recurrent cerebral microembolic events originating from the aortic atheromas.

Findings:

  • Surgical excision and replacement of the affected aortic arch segment with a Dacron graft successfully eliminated embolic signals.
  • Postoperatively, all cerebrovascular events ceased, and anticoagulation was discontinued.
  • The patient demonstrated significant neurological recovery and remained well at 1-year follow-up.

Implications:

  • Resection of mobile aortic arch atheromas is a viable and effective treatment for preventing recurrent embolic strokes.
  • Increased identification of aortic atheromas via transesophageal echocardiography may elevate the importance of surgical intervention.
  • This approach offers a potential future strategy for managing patients with atheroma-induced cerebrovascular disease.