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Multinodular pilomatrixoma.

Raquel S Simón¹, Evaristo Sánchez-Yus

¹Department of Dermatology, Investigation Unit of the Hospital Clínico San Carlos, Facultad de Medicina, Universidad Complutense, Madrid, Spain.

Dermatology (Basel, Switzerland)

|February 9, 2002

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A rare pilomatrixoma, a skin tumor, was found in a 12-year-old girl. Histology revealed a multinodular cyst-like growth, similar to a tricholemmal cyst budding phenomenon.

Area of Science:

Dermatopathology
Pediatric Pathology
Histopathology

Background:

Pilomatrixoma is a benign skin tumor originating from hair matrix cells.
This case presents a rare multinodular variant of pilomatrixoma.
The differential diagnosis includes other adnexal neoplasms and cysts.

Observation:

A 6 x 3 mm hard deep nodule was surgically removed from a 12-year-old girl's cheek.
Histological examination revealed a multinodular, cyst-like proliferation.
Each nodule exhibited the characteristic structure and cytology of pilomatrixoma.

Findings:

The histological findings confirmed a diagnosis of pilomatrixoma.
The multinodular, cyst-like architecture was noted.
A comparison was drawn to the budding phenomenon observed in isthmus-catagen (tricholemmal) cysts.

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Implications:

This case expands the understanding of pilomatrixoma morphology.
Recognizing the multinodular variant is crucial for accurate diagnosis.
The comparison with tricholemmal cysts may aid in differentiating similar lesions.