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Adrenal histoplasmosis.

S Gohar¹, A Sule, S Gaitonde

¹Department of Rheumatology, PD Hinduja National Hospital and Medical Research Centre, Veer Savarkar Marg, Mahim, Mumbai.

The Journal of the Association of Physicians of India

|February 12, 2002

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A diabetic patient recovered fully after treatment for bilateral adrenal masses caused by histoplasmosis. This case highlights histoplasmosis as a treatable cause of adrenal masses in immunocompromised individuals.

Area of Science:

Infectious Diseases
Endocrinology
Medical Mycology

Background:

Diabetes mellitus is a common comorbidity associated with increased susceptibility to infections.
Adrenal masses can present with diverse etiologies, necessitating thorough investigation.

Observation:

A 60-year-old male with diabetes presented with persistent low-grade fever and significant weight loss over six weeks.
Imaging revealed bilateral adrenal masses, prompting further diagnostic evaluation.

Findings:

Biopsy confirmed the adrenal masses were caused by disseminated histoplasmosis, a fungal infection.
The patient was treated with itraconazole, an antifungal medication.

Implications:

This case underscores the importance of considering opportunistic infections like histoplasmosis in the differential diagnosis of adrenal masses, particularly in diabetic patients.

Related Experiment Videos

Prompt diagnosis and appropriate antifungal therapy, such as itraconazole, can lead to complete recovery from disseminated histoplasmosis affecting the adrenal glands.