Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Minor diterpenoids from Halimium viscosum.

J G Urones1, M J Sexmero, F A Hernandez

  • 1Departamento de Química Orgánica, Universidad de Salamanca, Spain.

Natural Product Letters
|February 13, 2002
PubMed
Summary

Two novel diterpenic acids featuring an ent-halimane skeleton were identified in Halimium viscosum. These compounds, isolated from aerial plant parts, expand the known diversity of natural diterpenoids.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Supplementing Silicoglycidol for the reduction of aflatoxin M<sub>1</sub> in milk and biomarkers of liver dysfunction in dairy cows.

JDS communications·2024
Same author

Prenylflavonoids and prenyl/alkyl-phloroacetophenones: synthesis and antitumour biological evaluation.

European journal of medicinal chemistry·2010
Same author

Microbial hydroxylation of sclareol by Rhizopus stolonifer.

Molecules (Basel, Switzerland)·2007
Same author

From labdanes to drimanes. Degradation of the side chain of dihydrozamoranic acid.

Molecules (Basel, Switzerland)·2007
Same author

Synthesis of novel antitumoural analogues of dysidiolide from ent-halimic acid.

Bioorganic & medicinal chemistry·2007
Same author

Synthesis of three marine natural sesterterpenolides from methyl isoanticopalate. First enantioselective synthesis of luffolide.

The Journal of organic chemistry·2005

Area of Science:

  • Natural Product Chemistry
  • Organic Chemistry
  • Phytochemistry

Background:

  • Halimium viscosum is a plant species known to produce various secondary metabolites.
  • Diterpenoids, a class of natural products, often exhibit significant biological activities.
  • The Villarino de los Aires chemotype of H. viscosum was investigated for its chemical constituents.

Purpose of the Study:

  • To isolate and characterize new diterpenic acids from Halimium viscosum.
  • To elucidate the chemical structures of novel ent-halimane diterpenoids.
  • To contribute to the understanding of the phytochemical diversity of Halimium species.

Main Methods:

  • Extraction of secondary metabolites from the aerial parts of Halimium viscosum.
  • Chromatographic separation techniques for isolating diterpenic acids.

Related Experiment Videos

  • Spectroscopic methods (e.g., NMR, MS) for structure elucidation.

    • Main Results:

    • Isolation of two new diterpenic acids with an ent-halimane skeleton.
    • Identification of 13-oxo-14, 15-dinor-1(10),11E-ent-halimadien-18-oic acid and 15-hydroxy-1(10),13Z-ent-halimadien-18-oic acid.
    • These compounds were obtained as methyl esters.

    Conclusions:

    • The study successfully identified two previously unknown diterpenic acids from Halimium viscosum.
    • The findings expand the structural diversity of ent-halimane diterpenoids found in nature.
    • This research highlights the potential of H. viscosum as a source of novel natural products.