Related Experiment Videos
Towards the structure of the mammalian signal recognition particle
Klemens Wild1, Oliver Weichenrieder, Katharina Strub
1Biochemie-Zentrum (BZH), University of Heidelberg, Im Neuenheimer Feld 328, D-69120, Heidelberg, Germany.
Current Opinion in Structural Biology
|February 13, 2002
Abstract:
The signal recognition particle (SRP) is a ubiquitous ribonucleoprotein particle involved in the co-translational targeting of proteins to membranes. Crystal structures are now available for three protein-RNA subcomplexes from the SRP, which give insights into fundamental aspects of protein-RNA recognition, the assembly of stable ribonucleoprotein particles and the mechanism of action of the SRP.