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Updated: Aug 14, 2026

Optical Clearing and Imaging of Immunolabeled Kidney Tissue
Published on: July 22, 2019
Hematoxylin bodies: their appearance in renal tubular epithelium
Abstract:
Hematoxylin bodies, the pathognomonic light microscopic feature of systemic lupus erythematosus commonly found in renal glomeruli affected with active nephritis, are described in renal tubular epithelium. Formerly thought to be the result of "L.E. transformation" of these cells, a proposed mechanism of this phenomenon is that hematoxylin space are phagocytosed by tubular epithelial cells. This would explain the observation in the case presented and also that of the single previous report of this unusual feature.
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