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Related Experiment Videos

Recognizing periodic alternating nystagmus.

J Shallo-Hoffmann1, P Riordan-Eva

  • 1College of Optometry, Nova Southeastern University, Fort Lauderdale, Florida 33328-2018, USA. shoffman@nova.edu

Strabismus
|February 13, 2002
PubMed
Summary
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Periodic alternating nystagmus (PAN) is a cyclic eye movement disorder. Recognizing congenital or acquired PAN is crucial for appropriate treatment, including surgery or medication.

Area of Science:

  • Ophthalmology
  • Neurology
  • Neuroscience

Background:

  • Periodic alternating nystagmus (PAN) is a rare form of involuntary eye movement.
  • It is characterized by a cyclical shift in the direction of nystagmus.
  • PAN can be congenital or acquired, often linked to cerebellar dysfunction.

Purpose of the Study:

  • To aid clinicians in recognizing both congenital and acquired forms of PAN.
  • To emphasize the clinical significance of identifying PAN.
  • To review current understanding and treatment options for PAN.

Main Methods:

  • Review of recent studies utilizing eye movement recordings.
  • Analysis of congenital PAN frequency in patients with congenital nystagmus.
  • Examination of waveform characteristics and foveation dynamics.

Related Experiment Videos

  • Assessment of surgical and pharmacological interventions.

    • Main Results:

    • Congenital PAN occurs with notable frequency in patients with congenital nystagmus.
    • Specific waveform characteristics and the role of foveation time in head turn alternation are described.
    • Acquired PAN is typically associated with cerebellar disease and causes oscillopsia.
    • Unlike other acquired nystagmus, acquired PAN shows good response to drug therapy.

    Conclusions:

    • Accurate identification of congenital PAN is vital for surgical planning in cases of anomalous head posture.
    • Acquired PAN, often indicative of cerebellar disease, necessitates prompt diagnosis due to its potential for oscillopsia.
    • PAN management strategies vary, with surgery for congenital forms and medication for acquired forms showing promise.