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Variant mannose-binding lectin genotypes and outcome in early versus late rheumatoid arthritis: comment on the

Niels A Graudal1, Peter Garred, Hans O Madsen

  • 1Gentofte University Hospital, Denmark.

Arthritis and Rheumatism
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PubMed
Abstract

No abstract available in PubMed .

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Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...