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Vegetative pyoderma gangrenosum in chronic renal failure.
M Goto1, O Okamoto, S Fujiwara
1Department of Dermatology, Oita Medical University, 1-1 Idaigaoka, Hasama-machi, Oita-gun, Oita 879-5593, Japan. gotomizu@oita-med.ac.jp
The British Journal of Dermatology
|February 14, 2002
Summary
This case study highlights a rare vegetative pyoderma gangrenosum variant in a hemodialysis patient. The condition presented as painful leg nodules, successfully treated with corticosteroids and supportive care.
Area of Science:
- Dermatology
- Nephrology
Background:
- Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis.
- It presents with various clinical forms, including ulcerative, pustular, bullous, and vegetative.
Observation:
- A 58-year-old woman on hemodialysis for 10 years developed painful, recurrent erythematous nodules on her legs.
- Lesions featured sinus formation and bloody pus discharge, with negative bacterial/fungal cultures.
- Histopathology showed neutrophilic abscesses and palisading granuloma.
Findings:
- The patient's lesions healed with supportive care and corticosteroids, leaving cribriform scars.
- The clinical presentation and histopathology suggest a possible vegetative form of pyoderma gangrenosum, despite the absence of ulceration.
Implications:
- This case expands the understanding of pyoderma gangrenosum variants, particularly in patients with chronic renal failure.
- Recognizing atypical presentations is crucial for timely diagnosis and management of pyoderma gangrenosum.