Related Experiment Videos
Acantholytic dyskeratotic epidermal nevus: a rare histopathologic feature
J Mazereeuw-Hautier1, I Thibaut, J L Bonafé
1Service de Dermatologie du Professeur Bonafé, Hôpital Rangueil, Toulouse, France. mazereeuw-hautier.j@chu-toulouse.fr
Journal of Cutaneous Pathology
|February 14, 2002
Summary
This study presents a rare case of acantholytic dyskeratotic epidermal nevus in a child. This congenital skin condition features characteristic histologic findings, aiding in diagnosis.
Area of Science:
- Dermatology
- Histopathology
Background:
- Epidermal nevus is a congenital skin malformation presenting as verrucoid, scaly plaques.
- Histologic variations exist, including acantholytic dyskeratosis, which is rarely observed.
Observation:
- A 3-year-old girl presented with asymptomatic, linear, keratotic, and scaly lesions on her left side since birth.
- Lesions followed Blaschko's lines, a pattern typical for epidermal nevi.
Findings:
- Biopsies showed acanthosis, papillomatosis, hyperkeratosis, and suprabasal clefting with acantholysis.
- Individual dyskeratotic cells (corps ronds et grains) were noted in the epidermis, confirming acantholytic dyskeratosis.
- The findings were consistent with epidermal nevus, differentiating it from linear Darier's disease.
Implications:
- This case adds to the limited literature on acantholytic dyskeratotic epidermal nevus.
- Recognizing this rare histopathologic feature is crucial for accurate diagnosis and management of congenital skin conditions.