Related Experiment Video
Updated: Oct 2, 2026

Assessment of the Acute Inhalation Toxicity of Airborne Particles by Exposing Cultivated Human Lung Cells at the Air-Liquid Interface
Published on: February 23, 2020
The ability of breathing system filters to prevent liquid contamination of breathing systems: a laboratory study
1Department of Anaesthetics and Intensive Care Medicine, University of Wales College of Medicine, Heath Park, Cardiff CF14 4XN, UK. wilkes@cf.ac.uk
Abstract:
The ability of 29 different breathing system filters (five pleated hydrophobic and 24 electrostatic) to prevent the passage of water was assessed. Five, 10 or 20 ml of water was added on to the patient side of the filter during ventilation of a patient model with the filter layer orientated either horizontally or vertically. Water did not pass through the filter layer during any of the 30 tests on the pleated hydrophobic filters. In contrast, water passed through the filter layer in 39 of the 144 tests on the electrostatic filters (27%; 95% CI for difference between the filter types 14-35%; p = 0.0004). For electrostatic filters, a smaller internal volume, a larger volume of water added, and having the filter layer horizontal rather than vertical all significantly increased the probability of water penetration. Although pleated hydrophobic filters would protect the breathing system against liquid contamination, electrostatic filters can also be used, provided the internal volume is chosen appropriately and the filter layer is vertical.
Related Concept Videos
Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
Filtration
Physical Methods for Controlling Microbial Growth: Radiation and Filtration
Breathing
External and Internal Respiration

