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Papillary glioneuronal tumor--a new tumor entity
H Broholm1, F F Madsen, A A Wagner
1Laboratory of Neuropathology, Copenhagen University Hospital, Rigshospitalet, Denmark. hbroholm@rh.dk
Clinical Neuropathology
|February 16, 2002
Summary
A rare papillary glioneuronal tumor was found in a teen's frontal lobe after a concussion caused seizures. Complete surgical removal resulted in no recurrence, indicating an indolent nature for this brain tumor.
Area of Science:
- Neuro-oncology
- Neurosurgery
- Neuropathology
Background:
- Glioneuronal neoplasms are a diverse category of central nervous system (CNS) tumors.
- These tumors exhibit characteristics of both glial and neuronal cells with variable differentiation.
- Recent research has identified novel variants within this tumor group.
Observation:
- A 16-year-old male presented with seizures following a traumatic brain injury.
- Magnetic Resonance (MR) imaging revealed a complex cystic and solid tumor in the left frontal lobe.
- The tumor showed irregular but defined borders with contrast enhancement in its solid components.
Findings:
- Histopathological examination confirmed the tumor as a papillary glioneuronal tumor.
- The tumor demonstrated an indolent behavior.
- Gross total resection was achieved with no signs of recurrence.
Implications:
- This case highlights a rare variant of glioneuronal tumors.
- Papillary glioneuronal tumors may present with neurological symptoms like seizures.
- Complete surgical resection appears to be an effective treatment for achieving long-term remission.