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Astroblastoma: radiologic-pathologic correlation and distinction from ependymoma.
John D Port1, Daniel J Brat, Peter C Burger
1Neuroradiology Division, Johns Hopkins Hospital, Baltimore, MD, USA.
AJNR. American Journal of Neuroradiology
|February 16, 2002
Summary
Astroblastoma is a rare glial tumor with a distinct appearance on brain imaging. Understanding its typical features aids in accurate neuroradiologic diagnosis.
Area of Science:
- Neuro-oncology
- Radiology
- Pathology
Background:
- Astroblastoma is an uncommon primary glial tumor.
- It presents with specific neuroradiologic characteristics.
Purpose of the Study:
- To describe the typical imaging features of astroblastoma.
- To enhance diagnostic accuracy for neuroradiologists.
Main Methods:
- Review of neuroradiologic images of confirmed astroblastoma cases.
- Correlation of imaging findings with histopathological data.
Main Results:
- Astroblastomas are typically large, lobulated, peripheral, supratentorial masses.
- They exhibit a solid and cystic appearance with a bubbly solid component.
- Isointense T2 signal to gray matter and punctate calcifications are common.
- Minimal vasogenic edema and infiltration are noted relative to tumor size.
Conclusions:
- Astroblastoma has a characteristic appearance on neuroradiologic imaging.
- Familiarity with these features is crucial for neuroradiologists.
- This aids in differentiating it from other brain tumors.