Related Experiment Videos
Multiple myeloma involving the thyroid cartilage: case report
Jacob Sosna1, B Simon Slasky, Ora Paltiel
1Department of Radiology, Hadassah Hebrew University Hospital, Jerusalem, Israel.
AJNR. American Journal of Neuroradiology
|February 16, 2002
Summary
Multiple myeloma rarely affects the thyroid cartilage, causing airway obstruction. This case highlights calcified matrix as a new sign of this rare extraosseous myeloma manifestation.
Area of Science:
- Oncology
- Radiology
- Otolaryngology
Background:
- Multiple myeloma is a rare plasma cell malignancy.
- Extraosseous involvement, while known, is uncommon.
- Thyroid cartilage involvement presents unique diagnostic challenges.
Observation:
- A patient presented with progressive airway obstruction.
- Computed tomography (CT) revealed diffuse thyroid cartilage calcifications.
- These calcifications were associated with multiple myeloma.
Findings:
- The case demonstrates multiple myeloma infiltrating the thyroid cartilage.
- Calcified matrix was identified within the affected cartilage.
- Standard lytic bone lesions were also present but lacked calcification.
Implications:
- Calcified matrix in the thyroid cartilage is a newly recognized manifestation of extraosseous multiple myeloma.
- This finding aids in diagnosing rare myeloma presentations.
- Enhanced understanding of myeloma's diverse pathology is crucial.