Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Autoimmune chronic active hepatitis.

P J Johnson1

  • 1Department of Clinical Oncology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong.

Hong Kong Medical Journal = Xianggang Yi Xue Za Zhi
|March 1, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mental health and employment outcomes in working-age US adults, 2010-2019.

Occupational medicine (Oxford, England)·2024
Same author

Repeat hepatic resection versus radiofrequency ablation for recurrent hepatocellular carcinoma: retrospective multicentre study.

The British journal of surgery·2021
Same author

Effects of publication bias on conservation planning.

Conservation biology : the journal of the Society for Conservation Biology·2019
Same author

Multicentre validation of a clinical prognostic score integrating the systemic inflammatory response to the host for patients treated with curative-intent for colorectal liver metastases: The Liverpool score.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2019
Same author

Pharmacokinetics of intravenous lithium chloride and assessment of agreement between two methods of lithium concentration measurement in the horse.

Equine veterinary journal·2017
Same author

Electronic Prompts Can Reduce The Number Of Unnecessary Clotting Screens Ordered For Patients.

Acute medicine·2017
Same journal

Cholera outbreak in 1932 and a public education pamphlet on the prevention of cholera.

Hong Kong medical journal = Xianggang yi xue za zhi·2026
Same journal

The Hong Kong Hospital Authority reform: a historical perspective. Part 3: From organisation reform to improving clinical quality and population health.

Hong Kong medical journal = Xianggang yi xue za zhi·2026
Same journal

Medical history of Hong Kong. Part II: Healers in the maze: unravelling the myths of Kowloon Walled City practitioners.

Hong Kong medical journal = Xianggang yi xue za zhi·2026
Same journal

Practical aspects of interpreting N-terminal pro-B-type natriuretic peptide levels in diagnosing Kawasaki disease.

Hong Kong medical journal = Xianggang yi xue za zhi·2026
Same journal

Kidney health for all: caring for people, protecting the planet.

Hong Kong medical journal = Xianggang yi xue za zhi·2026
Same journal

Functional outcomes following mechanical thrombectomy beyond 6 hours after acute ischaemic stroke.

Hong Kong medical journal = Xianggang yi xue za zhi·2026
See all related articles

Autoimmune hepatitis is a liver disease diagnosed by histology and immunological markers. Immunosuppressive therapy, primarily with prednisolone and azathioprine, improves symptoms and survival with minimal side effects.

Area of Science:

  • Hepatology
  • Immunology
  • Internal Medicine

Background:

  • Autoimmune hepatitis (AIH) is a chronic liver disease recognized for nearly 50 years.
  • Typically affects young women presenting with acute liver illness, fatigue, joint pain, menstrual irregularities, and jaundice.
  • Diagnostic guidelines exist for research, but clinical diagnosis relies on histology and immunological markers.

Purpose of the Study:

  • To review the diagnosis and treatment of autoimmune hepatitis.
  • To highlight the efficacy and safety of immunosuppressive therapy.

Main Methods:

  • Diagnosis based on histological findings of chronic active hepatitis.
  • Identification of immunological features, including elevated immunoglobulin G and autoantibodies.
  • Absence of other known causes for the observed liver pathology.

Related Experiment Videos

Main Results:

  • Controlled trials in the 1970s demonstrated the effectiveness of immunosuppressive therapy.
  • Therapy improved both patient symptoms and overall survival rates.
  • Refined treatment protocols over 20 years have led to good prognoses.

Conclusions:

  • Autoimmune hepatitis is a manageable chronic liver condition.
  • Current treatment protocols using prednisolone and azathioprine offer good outcomes.
  • The prognosis for autoimmune hepatitis is favorable with appropriate medical management.