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Hapatitis A and E in Hong Kong.

J Y Lai1

  • 1Department of Medicine, Princess Margaret Hospital, Laichikok, Kowloon, Hong Kong.

Hong Kong Medical Journal = Xianggang Yi Xue Za Zhi
|March 1, 1997
PubMed
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Hepatitis A is common in Hong Kong, with adult cases rising due to travel and shellfish. Hepatitis E is emerging, especially risky for pregnant women. Vaccines exist for Hepatitis A, but not yet for Hepatitis E.

Area of Science:

  • Hepatology
  • Infectious Diseases
  • Public Health

Background:

  • Acute viral hepatitis remains a significant public health concern in Hong Kong.
  • Hepatitis A virus (HAV) constitutes the majority of reported viral hepatitis cases.
  • While childhood infections have decreased due to sanitation, adult cases of hepatitis A are increasingly prevalent.

Purpose of the Study:

  • To review the epidemiology of acute viral hepatitis in Hong Kong, focusing on Hepatitis A and Hepatitis E.
  • To highlight risk factors, diagnostic methods, and prevention strategies for Hepatitis A and E.
  • To inform healthcare providers and the public about the current status of these viral hepatitis infections.

Main Methods:

  • Review of epidemiological data on viral hepatitis in Hong Kong.

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  • Analysis of risk factors such as shellfish ingestion and international travel for Hepatitis A.
  • Discussion of clinical presentation, diagnosis (enzyme immunoassay for anti-HEV), and management of Hepatitis A and E.
  • Main Results:

    • Hepatitis A is the predominant cause of acute viral hepatitis, with increased adult infections linked to travel and shellfish.
    • Hepatitis E virus (HEV) is an emerging pathogen causing sporadic cases in Hong Kong and large outbreaks elsewhere.
    • Hepatitis E infection poses a high mortality risk, particularly in pregnant women.

    Conclusions:

    • Hepatitis A is preventable with an available inactivated vaccine.
    • Hepatitis E is a growing concern, necessitating traveler education, especially for pregnant women.
    • Further research and public health interventions are needed for Hepatitis E, as a vaccine is not yet available.