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Role of budesonide inhalation suspension in children with asthma

Kelly M West1, Nicole S Culhane

  • 1Nesbitt School of Pharmacy, Wilkes University, Wilkes-Barre, PA 18766-0997, USA. sparano@wilkes.edu

The Annals of Pharmacotherapy
|February 19, 2002
PubMed

Insights

Budesonide inhalation suspension (BIS) effectively treats pediatric asthma by reducing inflammation, improving lung function, and alleviating symptoms. This nebulized corticosteroid is a key option for children aged 1-8 with persistent asthma.

Area of Science:

  • Pediatric Pulmonology
  • Pharmacology
  • Respiratory Medicine

Background:

  • Asthma is a prevalent chronic inflammatory respiratory disease in children, affecting millions.
  • Corticosteroids are foundational in asthma management by reducing airway inflammation.
  • Effective delivery of medication is crucial for managing pediatric asthma symptoms.

Purpose of the Study:

  • To assess the efficacy of budesonide inhalation suspension (BIS) for treating asthma in pediatric patients.
  • To determine the role of BIS as a treatment option for children with persistent asthma.
  • To evaluate BIS in comparison to other inhalation devices for pediatric asthma management.

Main Methods:

  • A comprehensive literature search was conducted using Medline and article references.
  • The search encompassed studies published from 1966 to November 2000.
  • Keywords used were 'budesonide' and 'asthma' to identify relevant research.

Main Results:

  • Budesonide inhalation suspension (BIS) is the first nebulized corticosteroid available for asthma treatment.
  • BIS demonstrated effectiveness in reducing inflammation, a key factor in asthma.
  • The study highlights the potential of BIS to improve lung function and decrease symptoms in children.

Conclusions:

  • Budesonide inhalation suspension (BIS) is an effective treatment for reducing asthma symptoms and enhancing lung function in children.
  • BIS is recommended for children aged 1-8 years experiencing moderate to severe persistent asthma.
  • This therapy is particularly beneficial for pediatric patients who struggle with metered-dose inhalers or dry-powder inhalers.
Abstract

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