Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Anthrax: safe treatment for children.

Sandra Benavides1, Milap C Nahata

  • 1College of Pharmacy, Ohio State University, and Children's Research Institute, Children's Hospital, Columbus, OH, USA.

The Annals of Pharmacotherapy
|February 19, 2002
PubMed
Summary

Anthrax treatment guidelines for children are limited. Doxycycline and ciprofloxacin are recommended by the CDC for pediatric anthrax, despite potential risks and lack of extensive pediatric studies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Treatment Patterns and Barriers to Care Among U.S. Adults With Co-Occurring Substance Use Disorder and Mental Illness.

The American journal of psychiatry·2026
Same author

Efficacy and Safety of Combination Pharmacotherapies With Standard Diuretic Therapy in Acute Heart Failure: A Systematic Review and Meta-Analysis.

Cardiology in review·2026
Same author

Patterns of Dietary Supplement Use for Weight Loss Among U.S. Adults With Obesity: NHANES 2007-2020.

Journal of obesity·2026
Same author

Trends in Weight Loss Attempts and Strategies Among US Adolescents With Overweight or Obesity.

Obesity (Silver Spring, Md.)·2026
Same author

The global burden of mental and substance use disorders among adolescents and young adults.

Molecular psychiatry·2026
Same author

Patterns of psychotropic medication use, medication switching, augmentation, and non-persistence in adolescents and young adults with co-occurring psychiatric morbidities and opioid use disorder.

BMC psychiatry·2026

Area of Science:

  • Pediatric Infectious Diseases
  • Antimicrobial Therapy
  • Public Health

Background:

  • Limited data exists on anthrax infection treatment in children.
  • Children may face higher risks of severe anthrax disease compared to adults.
  • Current treatment recommendations for pediatric anthrax are based on adult data and limited pediatric evidence.

Purpose of the Study:

  • To review the current recommendations for anthrax treatment in children.
  • To discuss the safety and efficacy concerns of recommended antibiotics in pediatric populations.
  • To emphasize the importance of antibiotic use in potentially fatal anthrax infections in children.

Main Methods:

  • Review of Centers for Disease Control and Prevention (CDC) guidelines.
  • Analysis of existing literature on doxycycline and ciprofloxacin use in pediatric patients.
  • Evaluation of potential risks (e.g., dental staining, bone growth inhibition, cartilage toxicity) versus benefits.

Main Results:

  • Doxycycline and ciprofloxacin are recommended by the CDC for pediatric anthrax prophylaxis and treatment.
  • Doxycycline has potential dental and bone growth concerns in children under 8, though newer formulations may mitigate risks.
  • Ciprofloxacin has a narrow pediatric indication for inhaled anthrax exposure due to cartilage toxicity concerns in animal studies, but human data shows limited adverse events.

Conclusions:

  • Despite safety concerns and limited pediatric efficacy data, the benefits of using doxycycline and ciprofloxacin for anthrax outweigh the risks.
  • Antibiotic treatment is crucial for potentially fatal anthrax infections in children.
  • Further research on the safety and efficacy of anthrax treatments in pediatric populations is warranted.

Related Experiment Videos