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[Stromal leydig cell tumor coexisting with ascites].
G Czupkałło1, J A Jakowicki, W Baranowski
1Oddział Ginekologiczno-Połozniczy Szpitala SP ZOZ w Bełzycach.
Ginekologia Polska
|February 19, 2002
Summary
A rare stromal Leydig cell tumor (SLCT) in a 75-year-old woman caused virilization and hormonal imbalances. Surgical removal was complicated by venous thrombosis, with only slight symptom regression post-operation.
Area of Science:
- Gynecologic Oncology
- Endocrinology
- Pathology
Context:
- Stromal Leydig cell tumors (SLCTs) are exceptionally rare ovarian neoplasms.
- This case highlights a postmenopausal woman presenting with significant virilization symptoms.
Purpose:
- To report a rare case of stromal Leydig cell tumor (SLCT) in a postmenopausal woman.
- To describe the clinical presentation, hormonal profile, surgical management, and postoperative course.
Summary:
- A 75-year-old woman with hypertension and diabetes mellitus presented with signs of virilization, elevated testosterone, and low gonadotropins.
- Histopathological examination confirmed a stromal Leydig cell tumor with Reinke crystalloids.
- Postoperative complications included venous thrombosis, with minimal regression of virilization signs observed five weeks after surgery.
Impact:
- This case contributes to the limited literature on SLCTs, emphasizing their potential for significant hormonal and clinical manifestations.
- It underscores the importance of considering rare ovarian tumors in the differential diagnosis of virilization in postmenopausal women.
- The case also highlights potential postoperative complications and the need for vigilant monitoring.