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Published on: September 29, 2020
Noninvasive intraoperative monitoring of carbon dioxide in children: endtidal versus transcutaneous techniques
Mace A Nosovitch1, Joel O Johnson, Joseph D Tobias
1Departments of Child Health and Anesthesiology, The University of Missouri, Columbia, MO 65212, USA.
Insights
Transcutaneous (Tc) CO2 monitoring offers a more accurate intraoperative estimate of arterial CO2 in pediatric patients compared to end-tidal (PE) CO2 monitoring. Both methods are generally acceptable for monitoring PCO2 during anesthesia in children.
Area of Science:
- Anesthesiology
- Pediatric Critical Care
- Respiratory Physiology
Background:
- Intraoperative monitoring of carbon dioxide (CO2) is crucial in pediatric anesthesia.
- Noninvasive methods like transcutaneous (TcCO2) and end-tidal (PECO2) monitoring are used to estimate arterial CO2 (PaCO2).
- Accurate CO2 monitoring is essential for patient safety and management during surgery.
Purpose of the Study:
- To prospectively compare the accuracy of TcCO2 and PECO2 monitoring against PaCO2 in pediatric surgical patients.
- To evaluate the clinical acceptability of noninvasive CO2 monitoring methods in children.
- To determine which noninvasive method provides a more precise estimation of PaCO2 during intraoperative care.
Main Methods:
- Prospective study involving 30 pediatric patients (6 months to 15 years).
- Simultaneous measurements of arterial blood gases (PaCO2), end-tidal CO2 (PECO2), and transcutaneous CO2 (TcCO2).
- A total of 64 sample sets were analyzed for comparison.
Main Results:
- The difference between TcCO2 and PaCO2 was smaller and statistically more significant (P=0.038) than the PECO2 to PaCO2 difference.
- TcCO2 provided a more accurate estimate of PaCO2, with 49 of 64 sample sets showing a difference of 0.4 kPa (3 mmHg) or less.
- Linear regression showed a stronger correlation for TcCO2 (r2=0.8972) compared to PECO2 (r2=0.7676) versus PaCO2.
Conclusions:
- Both TcCO2 and PECO2 monitoring can provide clinically acceptable estimates of PaCO2 in pediatric patients.
- TcCO2 monitoring demonstrated slightly superior accuracy in estimating PaCO2 during intraoperative anesthetic care in children.
- These findings support the use of TcCO2 as a reliable noninvasive tool for monitoring CO2 levels in pediatric surgery.
Background:
The current study prospectively compares the accuracy of the intraoperative use of transcutaneous (Tc) and endtidal (PE) CO2 monitoring during surgical procedures in 30 paediatric patients, ranging in age from 6 months to 15 years (6.15 +/- 4.35 years) and in weight from 4.7 to 73 kg (24.9 +/- 18.2 kg).
Methods:
Following calibration and an equilibration time for the TcCO2 monitor, arterial blood gas samples were obtained as clinically indicated. A total of 64 sample sets (PaCO2, PECO2 and TcCO2) were obtained from the 30 patients.
Results:
The PECO2 to PaCO2 difference was 0.6-0.9 kPa (4.4 +/- 7.1 mmHg) while the TcCO2 to PaCO2 difference was 0.36-0.38 kPa (2.8 +/- 2.9 mmHg) (P=NS). The difference between the PaCO2 and PECO2 was 0.4 kPa (3 mmHg) or less in 37 of 64 sample sets while the difference between the PaCO2 and TcCO2 was 0.4 kPa (3 mmHg) or less in 49 of 64 sample sets (P=0.038). Linear regression analysis of PECO2 vs. PaCO2 revealed a slope of 0.434, r=0.8761, r2=0.7676. Linear regression analysis of TcCO2 vs. PaCO2 revealed a slope of 0.914, r=0.9472, r2=0.8972.
Conclusions:
Although in most circumstances, both noninvasive monitors of PCO2 provided a clinically acceptable estimate of PaCO2, TCCO2 provided a slightly more accurate estimate of PaCO2 during intraoperative anaesthetic care in children.
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